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Nucific Bio X4

Four-way support for a slimmer body and smoother digestion!

Four-way support for a slimmer body and smoother digestion!

Enjoy Bio X4, a powerful 4-way defensive strategy against appetite, cravings, digestion, and metabolism — in 1 easy-to-use formula! Who knew looking and feeling so great could be this easy?*

Bio X4 has everything you need to look and feel fantastic.


Bio X4 takes a multi-pronged approach to digestive health. Every capsule is packed with powerful, science-backed ingredients to help balance your digestive system, supercharge your metabolism, curb your unhealthy cravings, and help you achieve weight loss results that have eluded you for years.*

The secret? Pure, scientifically-studied ingredients.

Healthy weight begins with healthy digestion, so we designed Bio X4 to help you overhaul your system from the inside out. This product combines 4 formulas into 1 capsule: An advanced probiotic blend, a powerful “junk food” craving blocker, potent digestive enzymes, and a metabolic-boosting blend.*

Every capsule of Bio X4 is packed with powerful probiotics.

Bio X4 contains 5 unique probiotic strains — with 12 billion CFUs — to help ensure smoother, more comfortable digestion. Probiotic strains like Lactobacillus and Bifidobacterium nourish your gut with healthy bacteria and restore balance to your digestive system. Together, these powerful probiotics work to get your gut bacteria back in balance — so you aren’t troubled by embarrassing gas, uncomfortable bloating, or occasional emergency trips to the bathroom.*

Digestive enzymes help your body absorb key nutrients.

Did you know that the vital nutrients in your foods could be passing right through your body — without giving you any nutritional benefits? That’s why we included 3 powerful digestive enzymes in Bio X4, to help you absorb every bit of nutrition from every bite of food. These key enzymes — amylase, lipase, and bromelain — help break down protein, fats, and carbs in your food… into the nutrients you NEED to be healthy.*

Green tea extract helps supercharge your metabolism.

As you age, your metabolism tends to slow down — which can make it a lot harder to lose weight. So we added the powerful metabolism-booster EGCG, more commonly known as green tea extract, to help fire up your digestion. EGCG is a powerful “fat loss helper” that cranks up your metabolism and boosts your energy — to help you experience a slimmer, lighter body.*

Our powerful cravings blocker keeps you on track.

As you know, the biggest threat to successful weight loss is intense cravings that can make you reach for unhealthy junk food. That’s why every capsule of Bio X4 includes an unhealthy cravings-blocker called Caralluma Fimbriata — which has been shown to help ease junk food cravings, so you can achieve the body you want.*

How can you tell if Bio X4 is right for you?

This unique formulation can be effective at any age or weight, to improve digestion AND help you lose stubborn fat. Its natural ingredients allow it to be gentle on your system, while still providing powerful and noticeable results. This formulation is especially beneficial for those who wish to lose weight, or anyone who experiences uncomfortable bloating or irregular digestion.*

Each batch of Bio X4 is tested for purity, quality, and potency.

We designed Bio X4 to work like no other weight management supplement on the planet. Every ingredient was deliberately chosen for its potency and purity — so you can look AND feel slimmer, healthier, and better than you have in years.* Each 30-day supply is packaged in a high-quality amber glass jar, to ensure each capsule stays fresh, potent, and unaffected by excess light and air. Plus, every batch is third-party tested for purity and potency, to verify you receive exactly what you’ve paid for.

Stock up on multiple bottles to maximize your savings.

The majority of Bio X4 customers enjoy taking advantage of the discounted multi-bottle options. Our 3-bottle option is the most popular order option, but your highest savings will be on our 6-bottle option.

Every order is backed by our industry-leading guarantee.

To offer you peace of mind, your order is protected by our 90-Day Guarantee. This gives you a full 3 months to watch this powerful supplement take effect. If you’re not thrilled with your results, just send back the bottles (even if they’re empty) and we’ll refund your purchase price. Because the bottom line is — your satisfaction is our #1 priority. And if you’re not thrilled with your results, we don’t want you to pay. Simple as that.

*All individuals are unique. Your results can and will vary.

Manages “Junk” Cravings*

Bio X4 contains Caralluma Fimbriata, which has been shown to help ease unhealthy food cravings — a major step toward achieving the body you want. This cravings-control compound helps you say “no” to those snacks and unhealthy foods that can wreck your diet — and your waistline.

Promotes Weight Management*

Nucific Bio X4 also contains EGCG — a natural compound found in green tea, which has been shown in numerous studies to boost your metabolism and help your body burn more fat. This potent metabolism booster can help you achieve a slimmer, lighter body — while giving you the energy to enjoy every minute of every day.


Supports Smoother Digestion*

Bio X4 contains 12 billion CFUs, from 5 powerful Lactobacillus and Bifidobacterium probiotic strains, to help ensure smoother, more comfortable digestion. This specially-designed probiotic blend helps soothe your digestion, providing relief from gas, bloating, and other gastric issues.

The product also has 3 key digestive enzymes — amylase, lipase, and bromelain — to help break down the foods you eat, unlocking the nutrients and easing digestive issues. These potent enzymes help you break down food more efficiently, so you get more of the nutritional benefits from the foods you eat — and can enjoy better head-to-toe health.

Boosts Metabolism*

The unique probiotic formula in Nucific Bio X4 helps balance your gut bacteria, which can affect your metabolism and energy levels. EGCG — the potent compound in green tea — has also been found to boost metabolism, supercharge your digestive system, and help you enjoy more energy.

*All individuals are unique. Your results can and will vary.

Bio X4 Frequently Asked Questions

What are the main ingredients in Nucific Bio X4?

The ingredients in Bio X4 are:

Probiotic Blend – 4 Billion CFU/Capsule

Lactobacillus Blend:

  • L. acidophilus
  • L. rhamnosus
  • L. plantarum

Bifidobacterum Blend:

  • B. lactis
  • B. animalis

Digestive Enzyme Blend – 43mg

  • Amylase (from Aspergilus Oryzae)
  • Bromelain
  • Lipase (from Rhizopus Oryzae)

Weight Management Blend – 100mg

  • Green Tea Extract (50% EGCG)

Craving Control Blend – 166mg

  • SimalumaTM (Caralluma Fimbriata extract)

† At time of manufacture

Other ingredients: Vegetable Cellulose (capsule), Microcrystalline Cellulose, Stearic Acid, Silica

What is Nucific Bio X4?

Bio X4 is our 4-in-1 weight management probiotic that works to optimize your digestive system from the inside out. Each capsule is packed with 4 nutrients to help balance your digestive system, supercharge your metabolism, curb your cravings, and support healthy weight loss. It’s like getting 4 powerful formulas in 1 — which work together to help you look AND feel fantastic.*

How does Bio X4 work?

Healthy weight begins with healthy digestion, so we designed Bio X4 to help you overhaul your system from the inside out.


The secret is in our revolutionary 4-in-1 formula:*

  1. Digestive enzymes to ease digestion & maximize nutrient absorption
  2. Caralluma Fimbriata to curb cravings and help you slim down
  3. Green tea extract (EGCG) to supercharge your metabolism
  4. Potent probiotics to balance gut bacteria & alleviate digestive issues

Together, these 4 blends give your body everything it needs for smoother, more comfortable digestion, enhanced all-day energy, and advanced slimming support.

Who should take Bio X4?

Bio X4 is designed to optimize your overall digestive health — from the inside out. It’s a fantastic choice for anyone who wants to enjoy smoother digestion, a slimmer waistline, more regular bowel movements, and higher energy levels. The product’s unique formulation can be effective at any age or weight, to improve digestion AND help you lose stubborn fat. That said, this product is especially beneficial for those who wish to lose weight, or anyone who experiences uncomfortable bloating or irregular digestion.*

How many bottles of Bio X4 should I order?

The majority of our customers enjoy taking advantage of the discounted 3-bottle option. For those who wish to share Bio X4 with their families, we recommend investing in our even lower discounted 6-bottle option.

Does Bio X4 require refrigeration?

No. Each 30-day supply is packaged in a high-quality amber glass jar, to ensure each capsule stays fresh, potent, and unaffected by excess light and air. For this reason, the product does not require refrigeration.

How pure is Bio X4? Does it contain any known allergens?

This product is made up of pure, professionally-sourced ingredients. Every batch is tested for quality and purity at an independent, 3rd-party facility. We use gluten-free, allergen-free capsules. However, we recommend consulting with your own doctor before starting any new health program or nutritional supplement.

Is Bio X4 compatible with my diet?

Because every capsule of Bio X4 is 100% gluten-free and allergen-free, it is compatible with any diet. However, we always recommend talking to your own doctor or nutritionist before trying a new supplement or making changes to your diet — he or she will know what’s best for your unique dietary needs.

How do I take Bio X4?

For optimal results, take 1 capsule with each meal, 3 times per day. You can take up to 2 capsules per meal, but do not exceed 6 capsules a day. If you accidentally miss a serving, or even an entire day, just continue as normal the next day.

What will happen if I miss a day?

Preferably, you want to take Bio X4 consistently on a daily basis, to allow your body to build up a prime level of digestive enzymes, nutrients, and beneficial bacteria. If you happen to miss a serving, or even an entire day, just continue as normal the next day.

Does Bio X4 really work?

When we formulated Bio X4, we wanted to create a nutritional supplement that any man or woman could take to support their weight management, regardless of age, body type, or eating habits. Every capsule contains natural ingredients that are gentle on your system, while still providing noticeable results.


However, keep in mind that every digestive system is different — so results can vary from person to person. For best results, we suggest using Bio X4 consistently as directed on a daily basis. In the meantime, if you have any questions or concerns about Bio X4, our Customer Support team is standing by. Give us a call or send us an email, and we’ll be happy to help.

Bio X4 Results: How long will it take to notice a difference?

Everyone’s digestive system is different — and therefore, individual results will vary. We recommend allowing this product at least 30 days to fully get to work. Many users experience their best results after 60 days. For optimal results, we advise taking the recommended serving of 3 capsules on a daily basis, exercising regularly, and not overeating carbs and sweets. Video reviews online can help you to get a better idea of others’ experiences with this dietary supplement.

How can I get the most out of Bio X4?

The best way to maximize the slimming effects of Bio X4 is by taking it consistently 3 times per day, as well as combining it with regular exercise and a healthy diet. On its own, it’a is a fantastic tool for optimizing your digestive health. But if you take this supplement in addition to exercising and eating right, you’re going to see much more dramatic effects. 


For this reason, we recommend stocking up on multiple bottles — that way, you’ll be covered for months to come, without having to wait between shipments. Your biggest savings will be on our discounted 3-bottle or 6-bottle options.

Where to buy Bio X4: Is it online or in stores?

No, Bio X4 is not currently available in stores. At this time, Nucific is the only company selling it. Amazon and other online distributors do not carry it.

What if Bio X4 doesn’t work for me? Is there a guarantee?

We believe everyone can benefit from the digestion-supporting and energy-boosting ingredients in Bio X4. However, we recommend always speaking with your doctor before beginning this (or any) new health program or supplement.


That said, we also know that every individual body is different. So if this formula doesn’t meet your expectations, rest assured we’ve got you covered. Every order is covered by our 90-Day Refund Guarantee. That means you can use up the entire bottle — and if you’re unhappy for any reason, just send it back within 90 days. We’ll happily refund your purchase price, no questions asked.

So please — try it for yourself for a full 3 months. And if you’re not 100% thrilled with your results, we don’t want you to pay. Simple as that.


*All individuals are unique. Your results can and will vary.



Suggested Use

Take 1 capsule with each meal, 3x a day. Can take up to 2 capsules per meal, but do not exceed 6 capsules a day.


4.6 3570 Reviews


Apr 27 2021

WORKS great!


It has been the best digestive product I’ve bought in my life. […]


Apr 11 2021



My husband and I have been on it for a little over a month. We got rid of the high fructose foods. We are eating better and guess what? my husband lost five pounds and wow! couldn’t believe it. I, a senior, lost 13 pounds. We just got started. Thanks Amy Lee!


Mar 26 2021



I have to say I was skeptical, I watched a video I found while on instagram and said “why not” and I have never been so amazed by anything before. It is literally the best thing i’ve ever tried. After the first week, I just didn’t want to eat bad foods anymore and didn’t know why. Almost been a month […] I literally tell everyone I know having weight problems to try it. So thank you for this amazing product, you’ll want to get it monthly trust me(:


Mar 24 2021

It actually works!!!


I saw instant results when I started taking the pills. All my carvings stopped […] And 30 min twice or once a week for a jog definitely helped with my weight loss. So I highly recommend this product!!!


Feb 8 2021

Amazing Results... and quickly!


Not one to subscribe to just any weight loss program, I did some research and decided to give Bio-X4 a shot. Bio-X4 is the only product I’ve ever tried that actually works! I dropped weight with minimal changes to diet and zero exercise! The only drawback was I had to go buy some new skinny jeans ’cause the old ones were literally falling off – Justine


Nov 17 2020

Lost weight!


[…] It helped me curve cravings, slim my waist line and got rid of my bloating and discomfort. I got more active, and had more energy. I also began to care more about what I ate, and how much. This stuff works, and I will continue to purchase more!


Nov 13 2020

LOVE this Product!


I can’t say enough about this product! I read the reviews before I purchased and gave it a try. I didn’t know what to expect. It has been such a positive contribution to my everyday wellbeing and diet. First, I’d like to start off and tell you that I was having digestive issues for years. I was diagnosed with something referred to as SIBO, small intestinal bacteria overgrowth. In a nutshell, too much of the bad bacteria was wreaking havoc on my small intestine. This caused a lot of stomach pain, bloating, gas, indigestion, and constipation. The probiotic in this product along with a digestive enzyme has really helped put all theses symptoms to rest. Secondly, the craving blocker has worked amazingly well for me too! I used to eat a lot more sugar. I love it, as most do, but it was hurting my weight loss progress. I noticed a BIG difference in my cravings since taking this product. I no longer wanted to eat sugar and if I had a little, I didn’t feel out of control. Third, the appetite suppressant is real. I have noticed that I eat less and I didn’t really have to try too hard to do so. I realize that everyone is different and results may be different for everyone, but if you take this product consistently, eat a healthy diet and exercise, you will see and feel the results. After taking this product for about five months, I have lost about 6-7 pounds, have no more bloating, gas or constipation and I have more energy.


Oct 28 2020

Nucific BioX4


These product seems to be helping me maintain my weight. I have been taking it for six months now.


Sep 19 2020

Great product.


I am so pleased with how this product actually WORKS! […] I was inspired by Dr. Amy’s video, and she really came through with this product! Thank you so much, I was in misery for years, & this product has helped very much!


Feb 24 2020

It's Amazing


I have been taking this since early January because of the inspirational video that I saw Dr. Amy deliver – and I have been feeling great […] I have also been eating cleaner and exercising, but I honestly don’t think I could have done it without this product and also in conjunction with their probiotic. I can’t thank you all enough for helping me get my life back.

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