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Nucific Bio X4 - bio x4 reviews - dr amy lee bariatric physician
BIO X4 Supplement Facts Thumbnail


4-in-1 Weight Management Probiotic


When you’re trying to slim down, one of the biggest challenges is resisting the constant cravings you feel for fattening foods. To make matters worse, when you try to force yourself to cut calories, your metabolism slows down… and that makes your energy go down and your body fat go up. Not to mention, the change in diet often increases digestive problems.

What is BIO-X4? BIO-X4 is specifically designed to flip that situation on its head and help you…

  • Control those cravings that make you overeat
  • Boost your metabolism and burn more fat
  • Get the energy and nutrients you need from the food you eat
  • Feel more confident without gas and bloating after eating
nucific bio x4 reviews - lipase amylase bromelain - nucific reviews

Who Needs BIO-X4?

BIO-X4 can be helpful to anyone who is trying to slim down naturally without dangerous prescription drugs… without radical lifestyle changes… without impossible-to-maintain diets. If you are having trouble curbing that hunger and getting the body you deserve, try BIO-X4 for 90 days risk-free. If you are not 100% satisfied with your fat-loss results, increased energy levels, and improved digestive health… we’ll refund your money — no questions asked.

How BIO-X4 Works

With a unique blend of 4 different digestive and fat-loss enhancers, each capsule of BIO-X4 is designed to help you feel great while shrinking your waistline. The hunger-control power of Caralluma Fimbriata and the fat-burning capabilities of EGCG work in concert with the digestive boost of probiotics and digestive enzymes to help your body reach its full weight-loss potential. With your hunger down and your energy up, you can finally begin to see the progress you’ve been struggling to achieve in both your weight and your health. Users of BIO-X4 have reported…

  • Dramatically reduced junk food cravings
  • Losing stubborn fat that they couldn’t lose before
  • Significantly more energy throughout the day
  • Freedom from embarrassing gas, bloating, and irregular bathroom visits


Caralluma Fimbriata: Multiple studies have shown Caralluma Fimbriata extract to be a safe and powerful appetite suppressant. One study published in Appetite (May 2007) indicates that Caralluma extract helps suppress appetite and reduce waist circumference.1 EGCG is natural compound found in green tea. It has been shown in several studies to boost the body’s fat-burning activity. One study published in the American Journal of Clinical Nutrition indicated that EGCG quadrupled belly fat loss.2


Digestive Enzymes are tiny protein molecules that break down the foods you eat and unlock the nutrients for your body to absorb. As you get older, though, your production of these enzymes starts to slow down. BIO-X4 includes 3 key digestive enzymes to help you get the most from the food you eat:

  • Amylase: breaks down sugars
  • Lipase: breaks down fats
  • Bromelain: breaks down protein and helps calm intestinal irritation


Probiotics are friendly bacteria that help balance your gut. Your digestive system has both good and bad bacteria:

  • Good bacteria help you absorb the nutrients your enzymes unlock from your food.
  • Bad bacteria cause digestive problems and make you crave sugars, carbs, and other unhealthy foods.

Unfortunately, the American food supply is loaded with ingredients that feed the bad bacteria and wreak havoc on your digestive system. This Nucific probiotic can help you to fight off all that bad flora. The BIO X4 probiotic blend is powerful and provides 12 billion CFUs of friendly probiotic bacteria from 5 unique strains to re-balance your digestive system and increase energy levels.3 4

Suggested Use:

Take 1 capsule with each meal, 3x a day. Can be taken up to 2 capsules per meal, but do not exceed 6 capsules a day.

We Are Passionate About Product Safety:

Every capsule of BIO-X4 is packed with essential ingredients to control your cravings, enhance your digestion and metabolism, and help you achieve fat-loss results that have eluded you for years. Nucific reviews can help to confirm our dedication to our customers, their safety, and their overall health. However, just as important to us is what we do NOT put in the capsules.

  • No Lactose
  • No Fillers
  • 100% Pure Ingredients
  • Vegetarian Capsules


Nucific Biox4 was created by Dr. Amy Lee M.D. to help individuals struggling with weight loss and many of the digestive issues that can come along with strict diets. As a bariatric physician, she has worked first hand with patients who are having trouble losing weight, as well as the side effects they are having along the way. BIO X4 customers across the country have given their thanks to Dr. Amy Lee. BIO X4 was created specifically with them in mind. Doctor Amy Lee has board certifications in several areas including internal medicine, physician nutrition, and in obesity medicine specialty. She has specific interests in nutrition, wellness, and weight management. Dr. Amy Lee reviews are continuously full of praise from patients whose lives have been transformed. She understands the full spectrum of lifestyle changes that must occur for successful weight loss, and has made it her mission to help obese individuals attain their weight loss goals. With the help of Dr. Lee, weight loss is something that you can achieve. Working directly with Nucific, Dr. Amy Lee designed BIO X4 as a dietary supplement to help in the fight against fat – and also the side effects of major diet changes, which can be overwhelming for most anyone. But thanks to Dr. Amy Lee, weight loss can be a little bit easier with BIOX4.

BIO X4 Offers A Full 90-Day Money-Back Guarantee:

If you’re not 100% satisfied with the results, send back your order within 90 days for a full refund – no questions asked. You will be absolutely amazed at just how quickly your body can change. See the results for yourself…

Frequently Asked Questions

How Many Bottles Do You Recommend I Order?

The majority of our customers enjoy taking advantage of the discounted 3-bottle option. For those who wish to share with their families, we recommend investing in our even lower discounted 6-bottle option.

What’s In Bio X4?

BIO X4 Side Effects: What are they?

BIO X4 has no known side effects and is made up of pure ingredients. They only help your system. We use gluten-free, allergen-free capsules, so you can take them no matter what your diet restrictions may be.

How do I take BIO X4?

For optimal results, Take 1 capsule with each meal, 3x a day. Can be taken up to 2 capsules per meal, but do not exceed 6 capsules a day. Supplementing each meal with digestive help that assists in processing your food and extracting the maximum amount of nutrients gives your body the tools it requires to operate at its peak level of performance.

What will happen if I miss a day?

Preferably, you want to take BIO X4 consistently on a daily basis, to allow your body to build up a prime level of enzymes, nutrients, and beneficial bacteria. If you happen to miss a serving, or even an entire day, just continue as normal the next day.

BIO X4 Results: Does BIO X4 really work and how long will it take to notice a difference?

Everyone’s digestive system is a bit different. However, I feel you should give BIO X4 at least 30 days to fully get to work, and some users really start to see results after 60 days. I guarantee, if you are taking the recommended serving of 3 capsules on a daily basis, exercising regularly, and not overeating carbs and sweets, you will start seeing results within the first 1-2 months with BIO X4. Video reviews online can help you to get a better idea of others’ experiences with this dietary supplement.

Where to Buy BIO X4: Is it in stores or online?

Because BIO X4 is brand-new, it’s not available in stores. Currently, Nucific is the only company selling BIO X4. Amazon and other online distributors do not carry this product.


5 out of 5

Dec 8 2017   Probiotics Without Side Effects !!!

“Finally...a probiotic supplement that doesn't send you running to the bathroom with cramps, bloating & diarrhea. Because Bio-X4 gives you a small amount of probiotics with each meal instead of dumping a whole day's worth in at one time, everything is gently balanced. You get all the benefits without the irritation. That, combined with the digestive enzymes in Bio-X4 really help you digest your food well. This gives you so much more nutrition from your food that you have more energy & don't get as hungry. I tried a bunch of different probiotics before finding this one. Now I'm done looking. THANK YOU!!!”

*Results may vary

5 out of 5

Nov 5 2017   Incredible Product

“I am diabetic and on a ton of meds to control my diabetis including insulin. I always feel like crap, always, especially in the mornings. The first day I started taking BIO X4, I started feeling different by the end of the day - in a good way. My head was clearer and my body felt "refreshing" for the first time in many years. When I woke up the next morning, the time of day I feel the worst, I felt great for the first time in over 10 years. I usually am very skeptical about any product that professes to do the things as advertised, and I never leave reviews, but I was compelled to leave this review because of the significant difference this has already made in how my body feels after so many years of suffering. Thank you!”

*Results may vary

5 out of 5

Nov 4 2017   Love Bio-x4

“I no longer have bloat and belly fat is disappearing. I'm 71 yrs old and 30 lbs overweight. Tried everything under the sun to lose weight and just could not do it. I'm down 10 lbs and will continue to get 20 more off. This is a wonderful natural product that actually does what it advertised to do. I'm now on the automatic delivery and will have it available without forgetting to reorder.”

*Results may vary

5 out of 5

Oct 9 2017   Bio-X4 works

“This product has been a life saver for both my husband and I. We have both lost over 20 pounds and feel better than ever. We have more energy and really just love this product. It REALLY WORKS!!!!”

*Results may vary

5 out of 5

Sep 29 2017   This really works!

“I am very happy with the results. I have to say I was a bit skeptical at first, but it really does work if you suffer from digestive issues. I've lost a few pounds, but I'm not so concerned about that as much as I am about my digestive problems. It worked very quickly for me and I noticed a drastic improvement in just days after starting Bio-X4. I can live my life without worrying about how my meals will affect my digestion now, and I'm a much happier and healthier person. In my opinion this supplement is worth every penny.”

*Results may vary

5 out of 5

Sep 19 2017   Great Product

“This product is great! I have taken it for a month. I noticed after a few days my energy level had increased, no bloating and using the bathroom regularly. I also had decreased in appetite. This product is awesome!!! I will be ordering my 2nd bottle soon.”

*Results may vary

5 out of 5

Sep 11 2017   BIO-X4 and Probiotic

“This has the been the best I have ever taken... the bloating has been with me for so long I'm 79 yrs old never thought I would feel good again I've been on BIO for a month and feel good with it . Hopefully it works for the rest of my life 🙂 LaDonna”

*Results may vary

4 out of 5

Sep 11 2017   Nucific Review

“I really like this product. It has relieved my bloated belly. I am much more regular and have more energy. I also love the healthful tips that are sent regularly to my email. I am eating healthier; and losing a few pounds.”

*Results may vary

5 out of 5

Sep 11 2017   BIO-X4 has already started helping me!

“I've been taking BIO x4 for 5 weeks. Without going into detail, within the first few days I went from having inconsistent bathroom visits to regular. This alone, if it was the only benefit would make the product worth it. For those of you with similar issues, I know you would agree. I've also noticed my bloating problems and painful abdominal issues have nearly completely stopped. I'm a very satisfied customer so far. Thanks so much Nucific and Dr. Lee!”

*Results may vary

5 out of 5

Sep 11 2017   Bixo4

“This has been an awesome product! I plan to continue it thanks for the product. I'm feeling better!”

*Results may vary

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4.6 out of 5
4.6 OUT OF 5
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