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Nucific Bio X4 - bio x4 reviews - dr amy lee bariatric physician
BIO X4 Supplement Facts Thumbnail


4-in-1 Weight Management Probiotic


When you’re trying to slim down, one of the biggest challenges is resisting the constant cravings you feel for fattening foods. To make matters worse, when you try to force yourself to cut calories, your metabolism slows down… and that makes your energy go down and your body fat go up. Not to mention, the change in diet often increases digestive problems.

What is BIO-X4? BIO-X4 is specifically designed to flip that situation on its head and help you…

  • Control those cravings that make you overeat
  • Boost your metabolism and burn more fat
  • Get the energy and nutrients you need from the food you eat
  • Feel more confident without gas and bloating after eating
nucific bio x4 reviews - lipase amylase bromelain - nucific reviews

Who Needs BIO-X4?

BIO-X4 can be helpful to anyone who is trying to slim down naturally without dangerous prescription drugs… without radical lifestyle changes… without impossible-to-maintain diets. If you are having trouble curbing that hunger and getting the body you deserve, try BIO-X4 for 90 days risk-free. If you are not 100% satisfied with your fat-loss results, increased energy levels, and improved digestive health… we’ll refund your money — no questions asked.

How BIO-X4 Works

With a unique blend of 4 different digestive and fat-loss enhancers, each capsule of BIO-X4 is designed to help you feel great while shrinking your waistline. The hunger-control power of Caralluma Fimbriata and the fat-burning capabilities of EGCG work in concert with the digestive boost of probiotics and digestive enzymes to help your body reach its full weight-loss potential. With your hunger down and your energy up, you can finally begin to see the progress you’ve been struggling to achieve in both your weight and your health. Users of BIO-X4 have reported…

  • Dramatically reduced junk food cravings
  • Losing stubborn fat that they couldn’t lose before
  • Significantly more energy throughout the day
  • Freedom from embarrassing gas, bloating, and irregular bathroom visits


Caralluma Fimbriata: Multiple studies have shown Caralluma Fimbriata extract to be a safe and powerful appetite suppressant. One study published in Appetite (May 2007) indicates that Caralluma extract helps suppress appetite and reduce waist circumference.1 EGCG is natural compound found in green tea. It has been shown in several studies to boost the body’s fat-burning activity. One study published in the American Journal of Clinical Nutrition indicated that EGCG quadrupled belly fat loss.2


Digestive Enzymes are tiny protein molecules that break down the foods you eat and unlock the nutrients for your body to absorb. As you get older, though, your production of these enzymes starts to slow down. BIO-X4 includes 3 key digestive enzymes to help you get the most from the food you eat:

  • Amylase: breaks down sugars
  • Lipase: breaks down fats
  • Bromelain: breaks down protein and helps calm intestinal irritation


Probiotics are friendly bacteria that help balance your gut. Your digestive system has both good and bad bacteria:

  • Good bacteria help you absorb the nutrients your enzymes unlock from your food.
  • Bad bacteria cause digestive problems and make you crave sugars, carbs, and other unhealthy foods.

Unfortunately, the American food supply is loaded with ingredients that feed the bad bacteria and wreak havoc on your digestive system. This Nucific probiotic can help you to fight off all that bad flora. The BIO X4 probiotic blend is powerful and provides 12 billion CFUs of friendly probiotic bacteria from 5 unique strains to re-balance your digestive system and increase energy levels.3 4

Suggested Use:

Take 1 capsule with each meal, 3x a day. Can be taken up to 2 capsules per meal, but do not exceed 6 capsules a day.

We Are Passionate About Product Safety:

Every capsule of BIO-X4 is packed with essential ingredients to control your cravings, enhance your digestion and metabolism, and help you achieve fat-loss results that have eluded you for years. Nucific reviews can help to confirm our dedication to our customers, their safety, and their overall health. However, just as important to us is what we do NOT put in the capsules.

  • No Lactose
  • No Fillers
  • 100% Pure Ingredients
  • Vegetarian Capsules


Nucific Biox4 was created by Dr. Amy Lee M.D. to help individuals struggling with weight loss and many of the digestive issues that can come along with strict diets. As a bariatric physician, she has worked first hand with patients who are having trouble losing weight, as well as the side effects they are having along the way. BIO X4 customers across the country have given their thanks to Dr. Amy Lee. BIO X4 was created specifically with them in mind. Doctor Amy Lee has board certifications in several areas including internal medicine, physician nutrition, and in obesity medicine specialty. She has specific interests in nutrition, wellness, and weight management. Dr. Amy Lee reviews are continuously full of praise from patients whose lives have been transformed. She understands the full spectrum of lifestyle changes that must occur for successful weight loss, and has made it her mission to help obese individuals attain their weight loss goals. With the help of Dr. Lee, weight loss is something that you can achieve. Working directly with Nucific, Dr. Amy Lee designed BIO X4 as a dietary supplement to help in the fight against fat – and also the side effects of major diet changes, which can be overwhelming for most anyone. But thanks to Dr. Amy Lee, weight loss can be a little bit easier with BIOX4.

BIO X4 Offers A Full 90-Day Money-Back Guarantee:

If you’re not 100% satisfied with the results, send back your order within 90 days for a full refund – no questions asked. You will be absolutely amazed at just how quickly your body can change. See the results for yourself…

Frequently Asked Questions

How Many Bottles Do You Recommend I Order?

The majority of our customers enjoy taking advantage of the discounted 3-bottle option. For those who wish to share with their families, we recommend investing in our even lower discounted 6-bottle option.

What’s In Bio X4?

BIO X4 Side Effects: What are they?

BIO X4 has no known side effects and is made up of pure ingredients. They only help your system. We use gluten-free, allergen-free capsules, so you can take them no matter what your diet restrictions may be.

How do I take BIO X4?

For optimal results, Take 1 capsule with each meal, 3x a day. Can be taken up to 2 capsules per meal, but do not exceed 6 capsules a day. Supplementing each meal with digestive help that assists in processing your food and extracting the maximum amount of nutrients gives your body the tools it requires to operate at its peak level of performance.

What will happen if I miss a day?

Preferably, you want to take BIO X4 consistently on a daily basis, to allow your body to build up a prime level of enzymes, nutrients, and beneficial bacteria. If you happen to miss a serving, or even an entire day, just continue as normal the next day.

BIO X4 Results: Does BIO X4 really work and how long will it take to notice a difference?

Everyone’s digestive system is a bit different. However, I feel you should give BIO X4 at least 30 days to fully get to work, and some users really start to see results after 60 days. I guarantee, if you are taking the recommended serving of 3 capsules on a daily basis, exercising regularly, and not overeating carbs and sweets, you will start seeing results within the first 1-2 months with BIO X4. Video reviews online can help you to get a better idea of others’ experiences with this dietary supplement.

Where to Buy BIO X4: Is it in stores or online?

Because BIO X4 is brand-new, it’s not available in stores. Currently, Nucific is the only company selling BIO X4. Amazon and other online distributors do not carry this product.


5 out of 5

Nov 27 2018   Great results! Great service

“Thank you for a product that lives up to expectations! I lost 7 pounds in the first two months, but more importantly, I have more energy, MUCH better digestion and fewer cravings. I just ordered a three months supply (ordered on Friday and it was delivered Monday!). I am 69 years old and have struggled with weight gain for years - the probiotics have made a huge difference. Many thanks!”

*Results may vary

5 out of 5

Oct 24 2018   Bio X4 works for me

“Love Bio X4, this product has helped me reduce bloating, cravings and weight. I feel and look better inside and out. Even my Doctor is impressed with my results on bloating and lost weight. Thank you Dr. Amy for this wonderful Probiotic formula.”

*Results may vary

5 out of 5

Oct 7 2018   Best thing that has recently happened to me!!

“I have IBS-C and a sluggish gallbladder. I also don’t have to eat much to gain weight (I am usually 5 - 15 pounds overweight at one point or another). This product has changed my life. I go to the bathroom regularly now (daily!!!) starting two days after initiating the use of this product, something not accomplished with OTC medications or medications prescribed by my gastroenterologist. I stopped for a couple of days and went back to old habits so I started the product again and went back to regularity :). I am loosing weight slowly and have not had to maintain a strick low carb diet as I used to do to loose or maintain a certain weight. This product is a little pricy for me but it is worth every penny!!”

*Results may vary

5 out of 5

Aug 31 2018   I can't believe it! Something that actually works the way says it does.

“After just one week of consistently taking BIO X4 I feel better than before and I've noticed quite a few changes in my body... 1. I really do not crave sugar or sweeteners. I can drink my coffee black and feel good about it. 2. My bathroom visits are more consistent, and definitely different than before. 3. I feel like I sweat more easily, and burn calories + fat nearly all day, even inside an air conditioned home.”

*Results may vary

4 out of 5

Aug 26 2018   Really works

“I went to my doctor the other day and I’m losing weight with a minimal change in my diet. It’s given me a lot more energy, but the one thing I’ve noticed the most is I can concentrate longer and my memory is better. Gotta love that!”

*Results may vary

5 out of 5

Aug 12 2018   BioX4

“I really can’t live without BioX4, it has helped me so much and I now have my husband taking them! We are a very active couple and taking care of ourselves is our top priority! I have taken so many different weight loss vitamins through the years and NOTHING has worked like this! If you are thinking of trying these I highly suggest you become a member so that you can receive the best price! I love the fact that the Dr. Sends out specials frequently because it helps us to afford great health! I encourage you to try some of her other products which are super effective. I have gotten my best results taking BioX4 in conjunction with her other products!”

*Results may vary

4 out of 5

Jul 30 2018   Member

“Does help with cravings”

*Results may vary

5 out of 5

Jul 21 2018   Bio 4

“I have used this product for 2 years. It is a great product that helps with hunger cravings and keeps my abdominal bloating down. I have even got my co-workers hooked on the product and results.”

*Results may vary

5 out of 5

Jul 19 2018   BIOX4

“I love the Biox4. it is really working. I have noticed that I am slimming down around my waist and my thighs. I will continue to use this great product!!! Thanks!!!”

*Results may vary

5 out of 5

Jun 29 2018   100% IN LOVE AND AMAZED!

“Thank you so much doctor and staff that created this amazing product. I am 100% satisfied and happy, I can’t explain how well it works. It really is a wonderful product and it shows you changes on the second and third week already. This product is amazing! Thank you so much.”

*Results may vary

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4.6 out of 5
4.6 OUT OF 5
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