To see our FAQs regarding Covid-19, click here.

Shop Our Bestsellers

Quick View

Supports weight management in four ways.

What happens when you eat? Do you get uncomfortable and bloated shortly afterward? Do you suffer from heartburn minutes later? Do you get that “knotty, blocked” feeling at the top of your abdomen that won’t go away?


Quick View

Breakthrough Weight Management Probiotic Formula


Quick View

15 different strains of beneficial probiotic bacteria


Nucific is a proud sponsor of Action Against Hunger. AAH is a global organization leading the fight against global hunger by helping people around the world access clean water, healthy food, training, and healthcare.


See Why Our Customers Love Bio X4

Getting There!

“I still haven’t loss weight yet but my bloating has lessened tremendously and noticeably my complexion is clearing. That was huge for me. I have suffered with acne since I was a teenager and now that I’m in my late fifties, I was still experiencing flareups. Since I’ve been on Bio-X4, I’ve noticed a big improvement which is very exciting for me.”

– Sandy

Read more

Bio-X4 works for me

“Love Bio-X4, this product has helped me reduce bloating, cravings and weight. I feel and look better inside and out. Even my Doctor is impressed with my results on bloating and lost weight. Thank you Dr. Amy for this wonderful Probiotic formula.”

– Joy

Read more


“As a Telemarketer I do a lot of sitting at work and before taking Bio-X4 I used to snack a lot between meals. Not any more – Yeh !! It was a constant nibbling – but now I feel whole meal satisfied so drink more water. If I have a snack I also take an additional dose. Definitely feeling n seeing a reduction of belly fat volume with just the first bottle !! Thank you for this great combination !! Looking forward to taking other products you have for continued better health as I advance into my 70’s.”

– Elayn Glena

Read more

Bio-X4 has already started helping me!

“I’ve been taking Bio-X4 for 5 weeks. Without going into detail, within the first few days I went from having inconsistent bathroom visits to regular. This alone, if it was the only benefit would make the product worth it. For those of you with similar issues, I know you would agree. I’ve also noticed my bloating problems and painful abdominal issues have nearly completely stopped. I’m a very satisfied customer so far. Thanks so much Nucific and Dr. Lee!”

– Pablo Campos

Read more

Easy to take and works well

“I have been taking Bio-X4 for over 6 mos and have had and continue to have a good experience with it. I don’t crave diet sodas or sweets. I have lost weight but most importantly my indigestion and other GI issues have decreased and I feel much better.”

– Cindy

Read more


“I started taking Bio-X4 and I became more regular and with less gas than ever. When I take it before my meals it give me the peace of mind that I am doing something good for myself. I have recommended to my friends, the ones that want to shed a few pounds and the ones that complain about stomach problems.”

– Dora

Read more

Love the energy, regularity, and helps keep unwanted pounds off

“As a woman over 50, keep extra pounds off is extremely difficult. Bio-X4 is helping me to have energy to exercise, not eat quite as much, staying regular, so as I don’t have to use cleanses and keeping unwanted pounds off. At one time I thought I had gained, but found out I had actually lost weight. I have recommended this product to all my friends. It’s absolutely great.”

– Camille

Read more

Easy and effective!

“I feel so much healthier. I was struggling with IBS in combination with constipation. I have never been more regular in my life! Love this product and have recommended it to family and friends 🙂 It still amazes me how I no longer crave food all the time. I only feel hungry when it’s time to eat! Bio-X4 has been a game changer for me. Thank you!”

– Annie

Read more

Explore Nucific

Stay On Top of Your Weight Management

This powerhouse slimming formula helps increase your body’s fat reduction naturally.

Shop Now

Turn Unwanted Fat Into Full-Body Fuel

A powerful AMPK-activator designed to help burn unwanted fat.

Shop Now

Supercharge Your Metabolism

Maximize calorie-burn with this powerful thermogenic formula.

Shop Now

Text NUCVIP to 59703
for exclusive offers & updates

By signing up via text, you agree to receive recurring automated promotional and personalized marketing text messages (e.g. cart reminders) from Nucific at the cell number used when signing up. Consent is not a condition of any purchase. Reply HELP for help and STOP to cancel. Msg frequency varies. Msg & data rates may apply. View Terms & Privacy.

Recent Blogs

How to Unlock your Supplement’s Full Potential

How to Unlock your Supplement’s Full Potential

Sometimes, even when you're taking the BEST supplements possible, you may hit a progress plateau with your results… This could feel like you're experiencing a decrease in the effectiveness of your supplements. However, this is NOT the case! Typically, it's because...

read more
What Is The Difference Between Health And Wellness?

What Is The Difference Between Health And Wellness?

Knowing the difference between health and wellness can support building the foundations for well-being. When it comes to overall health, it’s about much more than illness. Learning about the various factors that contribute to health can allow you to create a holistic...

read more