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IMPORTANT NOTICE: We at Nucific want to support you as best we can during this challenging time. Our warehouse staff is working harder than ever to ship orders without delays, and taking extra safety precautions. And it's our honor to help you keep your health routine strong — so we're offering 20% off ALL of our regularly-priced products when you use code HEALTHY20 at checkout.

To learn more and see FAQs about what you can expect from Nucific during this time, click here.

Simple Nutrition

Supplements help maximize the benefits you get from the foods you eat. So our philosophy is that they should come from real food. That’s why all our nutritional supplements are extracted from whole fruits and vegetables.

Simple Nutrition

Supplements help maximize the benefits you get from the foods you eat.

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Quick View

Supports weight management in four ways.

What happens when you eat? Do you get uncomfortable and bloated shortly afterward? Do you suffer from heartburn minutes later? Do you get that “knotty, blocked” feeling at the top of your abdomen that won’t go away?


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Breakthrough Fat-Reducing Probiotic Formula


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15 different strains of beneficial probiotic bacteria


Nucific is proud to donate a portion of our proceeds from every purchase to Action Against Hunger. AAH is a global organization leading the fight against global hunger by helping people around the world access clean water, healthy food, training, and healthcare.


See Why Our Customers Love Bio-X4

Getting There!

“I still haven’t loss weight yet but my bloating has lessened tremendously and noticeably my complexion is clearing. That was huge for me. I have suffered with acne since I was a teenager and now that I’m in my late fifties, I was still experiencing flareups. Since I’ve been on Bio-X4, I’ve noticed a big improvement which is very exciting for me.”

– Sandy

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Bio-X4 works for me

“Love Bio-X4, this product has helped me reduce bloating, cravings and weight. I feel and look better inside and out. Even my Doctor is impressed with my results on bloating and lost weight. Thank you Dr. Amy for this wonderful Probiotic formula.”

– Joy

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“As a Telemarketer I do a lot of sitting at work and before taking Bio-X4 I used to snack a lot between meals. Not any more – Yeh !! It was a constant nibbling – but now I feel whole meal satisfied so drink more water. If I have a snack I also take an additional dose. Definitely feeling n seeing a reduction of belly fat volume with just the first bottle !! Thank you for this great combination !! Looking forward to taking other products you have for continued better health as I advance into my 70’s.”

– Elayn Glena

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Bio-X4 has already started helping me!

“I’ve been taking Bio-X4 for 5 weeks. Without going into detail, within the first few days I went from having inconsistent bathroom visits to regular. This alone, if it was the only benefit would make the product worth it. For those of you with similar issues, I know you would agree. I’ve also noticed my bloating problems and painful abdominal issues have nearly completely stopped. I’m a very satisfied customer so far. Thanks so much Nucific and Dr. Lee!”

– Pablo Campos

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Easy to take and works well

“I have been taking Bio-X4 for over 6 mos and have had and continue to have a good experience with it. I don’t crave diet sodas or sweets. I have lost weight but most importantly my indigestion and other GI issues have decreased and I feel much better.”

– Cindy

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“I started taking Bio-X4 and I became more regular and with less gas than ever. When I take it before my meals it give me the peace of mind that I am doing something good for myself. I have recommended to my friends, the ones that want to shed a few pounds and the ones that complain about stomach problems.”

– Dora

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Love the energy, regularity, and helps keep unwanted pounds off

“As a woman over 50, keep extra pounds off is extremely difficult. Bio-X4 is helping me to have energy to exercise, not eat quite as much, staying regular, so as I don’t have to use cleanses and keeping unwanted pounds off. At one time I thought I had gained, but found out I had actually lost weight. I have recommended this product to all my friends. It’s absolutely great.”

– Camille

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Easy and effective!

“I feel so much healthier. I was struggling with IBS in combination with constipation. I have never been more regular in my life! Love this product and have recommended it to family and friends 🙂 It still amazes me how I no longer crave food all the time. I only feel hungry when it’s time to eat! Bio-X4 has been a game changer for me. Thank you!”

– Annie

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Explore Nucific

Stay On Top of Your Weight Management

This powerhouse slimming formula helps increase your body’s fat reduction naturally.

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Probiotics to Help Your Gut

A comprehensive multi-strain probiotic blend to give you maximum results

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All-Natural Metabolic Support

Supercharge your metabolism and maximize calorie-burn with this thermogenic formula.

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