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Digestive Enzyme †
It’s time you put the enjoyment back in eating your favorite foods!
Nucific Digestive Enzyme helps your body smoothly and more efficiently process the foods you eat — so you can enjoy more of your favorite foods with less gastric distress… while getting the most from their vital nutrients.*
*All individuals are unique. Your results can and will vary.
$VIP Prices with a FREE Nucific Account!
Made With You In Mind
MFG in
the USA
GMP Certified
Facility
MFG in
the USA
How It Works
Supports Smoother Digestion†*
Our proprietary blend of 16 powerful digestive enzymes helps you break down every type of food, so your body can get the maximum nutritional benefits from those foods, while enjoying smoother, more comfortable digestion.
Amylase, Diastase, Glucoamylase, Beta-Glucanase, and 4 other enzymes help to gently break down carbs, grains, and starches, then convert them into usable energy.
Bacterial Protease, Fungal Protease, and Acid Protease break down proteins, which are critical for a healthy body, including your immune system, tissue, muscle, skin, hair, and nails.
Lactase helps break down dairy products, so you can experience less digestive distress.
Lipase breaks down fats, and helps promote healthy organ function.
Reduces Gas & Bloating†*
Alpha-Galactosidase helps break down gas-producing carbohydrates, easing digestive discomfort and allowing for smooth digestion.
Hemicellulase helps your body digest the soluble fiber found in plants. These valuable prebiotic fibers help support your gut’s healthy gut bacteria.
Cellulase breaks down cellulose (plant fiber), which eases digestive discomfort and helps free the nutrients found in fruits and vegetables so your body can absorb them.
*All individuals are unique. Your results can and will vary.
Learn More
How Many Bottles Do You Recommend I Order?
Many of our customers enjoy the discounted 3-bottle option to ensure they’ve got plenty of Digestive Enzyme on hand. If you plan on sharing with your family, we suggest purchasing the 6-bottle discount instead.
What's In Digestive Enzyme?
90 Capsules
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 90
| Amount Per Serving | % Daily Value |
|
| Amylase | 20,000 DU | ** |
| Diastase | 20,000 DP | ** |
| Bacterial Protease | 50,000 HUT | ** |
| Glucoamylase | 50 AGU | ** |
| Fungal Protease | 20,000 HUT | ** |
| Alpha-Galactosidase | 500 GALU | ** |
| Lactase | 750 ALU* | ** |
| Cellulase | 1,500 CU | ** |
| Beta-Glucanase | 50 BGU | ** |
| Lipase | 2,400 FIP | ** |
| Xylanase | 1,000 XU | ** |
| Pectinase | 50 endo-PGU | ** |
| Acid Protease | 20 SAPU | ** |
| Phytase | 10 FTU | ** |
| Invertase | 500 SU | ** |
| Hemicellulase | 500 HCU | ** |
** Daily Value (DV) not established
Is it gentle on the digestive system?
Digestive Enzyme is made from 100% gluten-free, allergen-free capsules and is designed to gently work with your body to help enhance your digestion. Nevertheless, always consult with a doctor before beginning any new supplements.
How do I take Digestive Enzyme?
For optimal results, please take 1-2 Digestive Enzyme capsules with a full glass of water with each meal. Do not exceed 6 capsules per day. We suggest that you start taking one capsule with each meal and wait to experience results before deciding to take two per meal.
What will happen if I miss a day?
If you miss a meal or a day, simply resume your Digestive Enzyme regimen at the following meal. You don’t need to take extra capsules to make up for the ones you’ve missed.
When can I experience results?
Everyone’s system is different, so we suggest waiting 60-90 days to experience the full benefits of Digestive Enzyme, including more comfortable digestion, reduced gas and bloating and more. It can take 1-2 months for the enzymes to fully populate your system, but if you keep up your regimen and eat balanced, nutritious meals, you can experience results.
Where to buy Digestive Enzyme: Is it online or in stores?
Digestive Enzyme is currently available for purchase online! Listings from 3rd party websites will not include our 90-day money-back guarantee.
*All individuals are unique. Your results can and will vary.
Suggested Use
Take 1 capsule with each meal. You may increase dosage to 2 capsules per meal. You should take at least 3 capsules per day. Do not take more than 6 capsules per day.
Reviews
*All individuals are unique. Your results can and will vary.
*All individuals are unique. Your results can and will vary.
Citations
- Peyrot des Gachons C, Breslin PA. Salivary Amylase: Digestion and Metabolic Syndrome. Curr Diab Rep. 2016;16(10):102. doi:10.1007/s11892-016-0794-7
- Antony N, Balachandran S, Mohanan PV. Immobilization of diastase α-amylase on nano zinc oxide. Food Chem. 2016;211:624-630. doi:10.1016/j.foodchem.2016.05.049
- Kumar P, Satyanarayana T. Microbial glucoamylases: characteristics and applications. Crit Rev Biotechnol. 2009;29(3):225-255. doi:10.1080/07388550903136076
- Celestino KR, Cunha RB, Felix CR. Characterization of a beta-glucanase produced by Rhizopus microsporus var. microsporus, and its potential for application in the brewing industry. BMC Biochem. 2006;7:23. Published 2006 Dec 5. doi:10.1186/1471-2091-7-23
- López-Otín C, Bond JS. Proteases: multifunctional enzymes in life and disease. J Biol Chem. 2008;283(45):30433-30437. doi:10.1074/jbc.R800035200
- Dajani EZ, Dajani NE, Shahwan TG. Over-the-Counter Drugs. In: Encyclopedia of Gastroenterology. Elsevier; 2004.
- Pirahanchi Y, Sharma S. Biochemistry, Lipase. [Updated 2021 Jul 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537346/
- Di Stefano M, Miceli E, Gotti S, Missanelli A, Mazzocchi S, Corazza GR. The effect of oral alpha-galactosidase on intestinal gas production and gas-related symptoms. Dig Dis Sci. 2007;52(1):78-83. doi:10.1007/s10620-006-9296-9
- Yi Y. Tiny Bugs Play Big Role: Microorganisms’ Contribution to Biofuel Production. In: Advances in 2nd Generation of Bioethanol Production. Woodhead Publishing; 2021.
- Image gallery gateway. Image: New Cellulase Enzymes Dramatically Reduce Costs of Plant Biomass Breakdown: R&D 100 Award. https://public.ornl.gov/site/gallery/detail.cfm?id=143.
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LOUIE
Apr 15 2025
Good
Product seems to be working well I will continue to use it
JEAN-GARDEL THEODORE
Nov 14 2024
Nucific Digestive Enzyme
It was excellent. I have more energy. I feel it especially when I workout. Thank you for a great product.
KATIE
Oct 6 2024
Pretty good
I’m not sure if this was really necessary on top of using Bio X4 but I do feel like the digestive enzymes help with bloating.
BEV MURRAY
Sep 29 2024
Slow and Steady
Taking Digestive Enzyme has made me feel thinner and brave enough to step on the scales. I hadn’t gained the weight I thought I had! It doesn’t work quickly for me, but it does keep working so I don’t feel the need to take it before every meal.
PATRICK KENNON
Sep 27 2024
Nucific Digestive Enzyme
This product seems to be working as advertised (as best as I can tell). My stomach problems have been relieved.
TIFFANY TRAWICK
Apr 9 2024
Look this!
Very gassy at first but then everything comes together and my gut health is under control using Nucific products ❤️Thanks Amy!
SUSAN FRIES
Apr 8 2024
LESS BLOATING!
I have been using Bio X 4 for quite a few years. It settles my digestive issues and is particularly helpful when it comes to bloating. I use it as directed, 1 before each meal. It works great! It’s a reliable product.
PATRICIA RAHTJEN
Apr 1 2024
Nucific Digestive Enzyme
I have been using this for only a couple of weeks at most but I have less stomach discomfort and upset. I still have some gas but don’t feel as bloated. I am pleased and hope that I have more good stomach bacteria.
LAURIE LEE
Jan 16 2024
Feel better
I have lost a few pounds and feel better, with better digestive health. I am able to fit into my pants much better.
ADELE RIFFE
May 24 2023
Digestive Enzyme works for me!
I take A LOT of probiotics on a daily basis – the Bio-X4, the Nighttime Slimming Complex, the Deep Cell Activator, and the Pro Body Trim. But when I began the Digestive Enzyme, everything began to be more efficient! My digestion is EXCELLENT! Thank you, Dr. Lee!