Nucific Bio-X4 †
Four-way support for a slim body and smoother digestion!
Enjoy Bio-X4, a powerful 4-way defensive strategy against unhealthy cravings, digestive issues, and metabolism — in 1 easy-to-use formula! Who knew looking and feeling so great could be this easy?*
*All individuals are unique. Your results can and will vary.
$VIP Prices with a FREE Nucific Account!
*All individuals are unique. Your results can and will vary.

Manages “Junk” Cravings†*
Bio-X4 contains Caralluma Fimbriata, which has been found to help ease unhealthy food cravings — a major step toward achieving the body you want. This cravings-control compound helps you say “no” to those snacks and unhealthy foods that can wreck your diet — and your waistline.

Promotes Weight Management†*
Nucific Bio-X4 also contains EGCG — a natural compound found in green tea, which has been found in numerous studies to boost your metabolism. This potent metabolism booster can help you achieve a slimmer, lighter body — while giving you the energy to enjoy every minute of every day.

Supports Smoother Digestion†*
Bio-X4 contains 12 billion CFUs, from 5 powerful Lactobacillus and Bifidobacterium probiotic strains, to help ensure smoother, more comfortable digestion. This specially-designed probiotic blend helps soothe your digestion, helping provide relief from gas, bloating, and other gastric issues.
The product also has 3 key digestive enzymes — amylase, lipase, and bromelain — to help break down the foods you eat, unlocking the nutrients and easing digestive issues. These potent enzymes help you break down food efficiently, so you get more of the nutritional benefits from the foods you eat — and can enjoy better head-to-toe health.

Boosts Metabolism†*
The unique probiotic formula in Nucific Bio-X4 helps balance your gut bacteria, which can affect your metabolism and energy levels. EGCG — the potent compound in green tea — can help boost metabolism, supercharge your digestive system, and help you enjoy more energy.
*All individuals are unique. Your results can and will vary.
Bio-X4 Frequently Asked Questions
What are the main ingredients in Nucific Bio-X4?
Bio-X4 combines four key ingredient blends: Green tea extract (EGCG), Caralluma Fimbriata, 5 potent probiotics, and 3 key digestive enzymes. Here is a list of the main ingredients:
- Lactobacillus acidophilus
- Lactobacillus rhamnosus
- Lactobacillus plantarum
- Bifidobacterium lactis
- Bifidobacterium animalis
- Amylase
- Bromelain
- Lipase
- Green tea extract (50% EGCG)
- Slimaluma ™
90 Capsules
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 90
| Amount Per Serving | % Daily Value |
|
|---|---|---|
| Probiotic Blend:
Lactobacillus Blend: L. acidophilus Bifidobacterum Blend: B. lactis |
4 Billion CFU/Capsule† | ** |
| Digestive Enzyme Blend:
Amylase (from Aspergilus Oryzae) |
43 mg | ** |
| Weight Management Blend:
Green Tea Extract (50% EGCG) |
100 mg | ** |
| Craving Control Blend:
Slimaluma™ (Caralluma Fimbriata extract) |
166 mg | ** |
** Daily Value (DV) not established
† At time of manufacture
What is Nucific Bio-X4?
Bio-X4 is our 4-in-1 weight management probiotic that works to optimize your digestive system from the inside out. Each capsule is packed with 4 nutrients to help balance your digestive system, supercharge your metabolism, curb your unhealthy cravings, and support your weight loss efforts. It’s like getting 4 powerful formulas in 1 — which work together to help you look AND feel fantastic.*
How does Bio-X4 work?
Healthy weight begins with healthy digestion, so we designed Bio-X4 to help you overhaul your system from the inside out. The secret is in our revolutionary 4-in-1 formula:*
- Digestive enzymes to ease digestion & maximize nutrient absorption
- Caralluma Fimbriata to curb unhealthy cravings and help you achieve your weight loss goals
- Green tea extract (EGCG) to help supercharge your metabolism
- Potent probiotics to help balance gut bacteria & alleviate digestive issues
Together, these 4 blends help give your body everything it needs for smoother, more comfortable digestion, enhanced all-day energy, and slimming support.
Who should take Bio-X4?
Bio-X4 is designed to optimize your overall digestive health — from the inside out. It’s a fantastic choice for anyone who wants to enjoy smoother digestion, a slimmer waistline, smooth bowel movements, and higher energy levels. The product’s unique formulation can be effective at any age or weight, to improve digestion AND help you control your weight. That said, this product can be especially beneficial for those who wish to lose weight, or anyone who experiences uncomfortable bloating or irregular digestion.
How many bottles of Bio-X4 should I order?
The majority of our customers enjoy taking advantage of the discounted 3-bottle option. For those who wish to share Bio-X4 with their families, we recommend investing in our even lower discounted 6-bottle option.
Does Bio-X4 require refrigeration?
No. Each 30-day supply is packaged in a high-quality amber glass jar, to ensure each capsule stays fresh, potent, and unaffected by excess light and air. For this reason, the product does not require refrigeration.
How pure is Bio-X4? Does it contain any known allergens?
This product is made up of professionally-sourced ingredients. Every formula is tested for quality at an independent, 3rd-party facility. We use gluten-free, allergen-free capsules. However, we recommend consulting with your own doctor before starting any new health program or nutritional supplement.
Is Bio-X4 compatible with my diet?
Because every capsule of Bio-X4 is 100% gluten-free and allergen-free, it is compatible with any diet. However, we always recommend talking to your own doctor or nutritionist before trying a new supplement or making changes to your diet — he or she will know what’s best for your unique dietary needs.
How do I take Bio-X4?
For optimal results, take 1 capsule with each meal, 3 times per day. You can take up to 2 capsules per meal, but do not exceed 6 capsules a day. If you accidentally miss a serving, or even an entire day, just continue as normal the next day.
What will happen if I miss a day?
Preferably, you want to take Bio-X4 consistently on a daily basis, to allow your body to build up a prime level of digestive enzymes, nutrients, and beneficial bacteria. If you happen to miss a serving, or even an entire day, just continue as normal the next day.
Does Bio-X4 really work?
When we formulated Bio-X4, we wanted to create a nutritional supplement that any man or woman could take to support their weight management, regardless of age, body type, or eating habits. Every capsule contains natural ingredients that are gentle on your system, while still providing noticeable results. However, keep in mind that every digestive system is different — so results can vary from person to person. For best results, we suggest using Bio-X4 consistently as directed on a daily basis. In the meantime, if you have any questions or concerns about Bio-X4, our Customer Support team is standing by. Give us a call or send us an email, and we’ll be happy to help.
Bio-X4 Results: How long will it take to notice a difference?
Everyone’s digestive system is different — and therefore, individual results will vary. We recommend allowing this product at least 30 days to fully get to work. Many users experience their best results after 60 days. For optimal results, we advise taking the recommended serving of 3 capsules on a daily basis, exercising regularly, and not overeating carbs and sweets. Video reviews online can help you to get a better idea of others’ experiences with this dietary supplement.
How can I get the most out of Bio-X4?
The best way to maximize the effects of Bio-X4 is by taking it consistently 3 times per day, as well as combining it with regular exercise and a healthy diet. On its own, it is a fantastic tool for optimizing your digestive health. But if you take this supplement in addition to exercising and eating right, you’re going to see much more dramatic effects. For this reason, we recommend stocking up on multiple bottles — that way, you’ll be covered for months to come, without having to wait between shipments. Your biggest savings will be on our discounted 3-bottle or 6-bottle options.
Where to buy Bio-X4: Is it online or in stores?
Bio-X4 is currently available for purchase online! Listings from 3rd party websites will not include our 90-day money-back guarantee.
What if Bio-X4 doesn’t work for me? Is there a guarantee?
We believe everyone can benefit from the digestion-supporting and energy-boosting ingredients in Bio-X4. However, we recommend always speaking with your doctor before beginning this (or any) new health program or supplement. That said, we also know that every individual body is different. So if this formula doesn’t meet your expectations, rest assured we’ve got you covered. Every order is covered by our 90-Day Refund Guarantee. That means you can use up the entire bottle — and if you’re unhappy for any reason, just send it back within 90 days. We’ll happily refund your purchase price, no questions asked. So please — try it for yourself for a full 3 months. And if you’re not 100% thrilled with your results, we don’t want you to pay. Simple as that.
*All individuals are unique. Your results can and will vary.
Suggested Use
Take 1 capsule with each meal, 3x a day. Can take up to 2 capsules per meal, but do not exceed 6 capsules a day.
*Some reviewers may have received compensation, such as free products or discounts, in exchange for their honest opinions. Individual results may vary.
*Some reviewers may have received compensation, such as free products or discounts, in exchange for their honest opinions. Individual results may vary.
Citations
- Katie J. Astell, Michael L. Mathai, Andrew J. McAinch, Christos G. Stathis, Xiao Q. Su. A pilot study investigating the effect of Caralluma fimbriata extract on the risk factors of metabolic syndrome in overweight and obese subjects: a randomised controlled clinical trial. Biomedical and Lifestyle Diseases (BioLED) Unit, College of Health and Biomedicine, Victoria University, Melbourne, Victoria 3021, Australia.
- Niedzielin, K., Kordecki, H., http://journals.lww.com/eurojgh/Abstract/2001/10000/A_controlled,_double_blind,_randomized_study_on.4.aspx
- M. Million, et al. Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii. International Journal of Obesity (2012) 36, 817–825; doi:10.1038/ijo.2011.153; published online 9 August 2011
- Rastmanesh R., et al. High polyphenol, low probiotic diet for weight loss because of intestinal microbiota interaction. Chemico-Biological InteractionsPublished 15 October 2010.
- Thielecke F, et al. Epigallocatechin-3-gallate and postprandial fat oxidation in overweight/obese male volunteers: a pilot study Eur J Clin Nutr. 2010 Jul;64(7):704-13. doi: 10.1038/ejcn.2010.47.
- Wang H., Effects of catechin enriched green tea on body composition. Obesity (Silver Spring). 2010 Apr;18(4):773-9. doi: 10.1038/oby.2009.256.
- Bitange Nipa Tochi, Zhang Wang, Shi – Ying Xu and Wenbin Zhang, 2008. Therapeutic Application of Pineapple Protease (Bromelain): A Review. Pakistan Journal of Nutrition, 7: 513-520.
- Date K, Satoh A, Iida K, Ogawa H. Pancreatic α-Amylase Controls Glucose Assimilation by Duodenal Retrieval through N-Glycan-specific Binding, Endocytosis, and Degradation. J Biol Chem. 2015 May 28. pii: jbc.M114.594937.
- Perano SJ,Couper JJ,Horowitz M, Martin AJ, Kritas S, Sullivan T, Rayner CK. Pancreatic enzyme supplementation improves the incretin hormone response and attenuates postprandial glycemia in adolescents with cystic fibrosis: a randomized crossover trial.J Clin Endocrinol Metab. 2014 Jul;99(7):2486-93. doi: 10.1210/jc.2013-4417. Epub 2014 Mar 26.
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DENNY HOLST
Oct 19 2025
Satisfied
It seems that I am experiencing positive changes in digestion. I have not lost any weight or belly mass but do feel better.
AMBER LLORENS
Oct 11 2025
slow but steady
Definitely seeing higher energy and focus. The weight doesn’t just drop off, its slow and steady, combined with a heathy diet results are sure!
KAREN
Sep 24 2025
2 months in
My cravings for sweets and carbs has diminished and I’m actually eating salads more frequently. I seem to have more energy and focus during the day.
CATERINA
Sep 23 2025
Very effective
I inly take 2/days and it helps a lot
LINDA FIELDS
Aug 25 2025
Bio X-4
I have been using nucific Bio X4 for about a year. It has done a great job of regulating my system and eliminating intestinal issues. I think it has also helped with weight management.
RHONDA
Aug 20 2025
Nucific is Terrific
I am beyond excited for my journey with Nucific!! I have only been taking Bio-x4 for one month and I am seeing results and people are noticing! My clothes are fitting looser, and I’ve had a few people ask if I’ve lost weight. I also feel generally overall better! I ordered more today and also ordered the nighttime supplement and the Microslim. I’m so excited to keep going and see my transformation!! Thank you for sharing a wonderful product!
LANCE
Jul 20 2025
Bio x
This formula give you energy and stops you over eating I have lost half a stone in a sort time I will keep using for a long time highly recommended
ROGER GEELHOOD
Jul 16 2025
Bio-X4 Review
I have been using Bio-X4 for approximately 2 years and have lost 30 pounds. I primarily use it as a probiotic. I find that it is less expensive than buying four different supplements separately when taking advantage of the discounts when they are available. I take one capsule before each meal.
TOM RICE
Jul 14 2025
Benefits
I feel more energetic and virile since starting this regimen
DONNA
Jun 14 2025
Bio-14
Does the job for me, no side effects at all just results!